Prof Karl Hoffmann

PhD

Chakroborty, A, Dankwa, B, Crusco, A, Forde-Thomas, JE, Abeysekara, S, Kiwanuka, Z, Ley, M, Davey, SD, Hollinshead, J, Bartholomew, B, Wild, C, Fenn, C, Thomas, DA, Holdsworth, P, Fisher, M, Baird, MS, Nash, RJ & Hoffmann, KF 2025, 'Anthelmintic evaluation of triterpenes derived from conifers (family Pinaceae) on the digenean parasite Fasciola hepatica', Fitoterapia, vol. 185, 106762. 10.1016/j.fitote.2025.106762

Rawat, M, Padalino, G, Adika, E, Okombo, J, Yeo, T, Brancale, A, Fidock, DA, Hoffmann, KF & Lee, MCS 2025, 'Quinoxaline-based anti-schistosomal compounds have potent anti-plasmodial activity', PLoS Pathogens, vol. 21, no. 2, e1012216. 10.1371/journal.ppat.1012216

Poon, V, Bailey, C, Carvalho, S, Patterson, S, Fyfe, JWB, Semenova, O, Wrigley, SK, Hopkins, E, Manohar, R, Drake, C, Kokubun, T, Boyle, J, Kvaerno, L, Lees, K, Hoffmann, KF, Forde-Thomas, J, Wyllie, S, Steele, J, Gilbert, IH & Tarver, GJ 2025, 'Use of P450 Enzymes for Late-Stage Functionalization in Drug Discovery', Journal of Medicinal Chemistry, vol. 68, no. 20, pp. 21479-21488. 10.1021/acs.jmedchem.5c01467

Padalino, G, Duggan, K, Mur, LAJ, Maillard, J-Y, Brancale, A & Hoffmann, KF 2024, 'Compounds Containing 2,3-Bis(phenylamino) Quinoxaline Exhibit Activity Against Methicillin-Resistant Staphylococcus aureus, Enterococcus faecalis, and Their Biofilms', MicrobiologyOpen, vol. 13, no. 6, e011. 10.1002/mbo3.70011

Stark, KA, Rinaldi, G, Costain, A, Clare, S, Tolley, C, Almeida, A, McCarthy, C, Harcourt, K, Brandt, C, Lawley, TD, Berriman, M, MacDonald, AS, Forde-Thomas, JE, Hulme, BJ, Hoffmann, KF, Cantacessi, C & Cortés, A 2024, 'Gut microbiota and immune profiling of microbiota-humanised versus wildtype mouse models of hepatointestinal schistosomiasis', Animal Microbiome, vol. 6, no. 1, 36. 10.1186/s42523-024-00318-3