YMR020W
(FMS1)
27.2.08
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SGD
Polyamine oxidase, converts spermine to spermidine, which is required for the essential hypusination modification of translation factor eIF-5A; also involved in pantothenic acid biosynthesis
go molecular function : amine oxidase activity (IDA, IGI, ISS)
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MIPS
similarity to Candida corticosteroid binding protein Cbp1p,
weak similarity to monoamine oxidases
.degradation of polyamines
amine oxidase (flavin-containing)
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KEGG
FMS1;
Fms1p;
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Literature examined:
Manas K. Chattopadhyay, Celia White Tabor, and Herbert Tabor*
Spermidine but not spermine is essential for hypusine biosynthesis and growth in Saccharomyces cerevisiae: Spermine is converted to spermidine in vivo by the FMS1-amine oxidase
PNAS November 25, 2003 vol. 100 no. 24 13869–13874