Supporting Online Material for the paper "The Automation of Science"
- Document describing Supporting Online
Material (PDF, 1.8M)
- Video demonstration of the Robot Scientist Adam at work. Robotlarge.mov, 47M, Quicktime format (If you need assistance to view this, we suggest VLC, a capable cross platform media player)
- The formalised description (in Datalog) of Robot Scientist
investigations. The Datalog files were generated using an ontology
"LABORS" (an is-a hierarchy, a set of relations, and a set of
restrictions for the classes) and a MySQL database which stores
structure, observations and results of the investigations. The Datalog
files are plain text, with a Prolog filename extension (.pl), and can
be viewed in any text editor. Relationships between research units
have been amended (17/5/10) and are now "has_part" relationships
rather than "has_proposition" relationships.
- Investigation into full automation of AAA experiments
- Investigation into novel science
- Automated study of genes encoding orphan enzymes
- Automated study of YDL052C: study_YDL052C.pl, study_YDL052C/
- Automated study of YDL168W: study_YDL168W.pl, study_YDL168W/
- Automated study of YER152C: study_YER152C.pl, study_YER152C/
- Automated study of YER183C: study_YER183C.pl, study_YER183C/
- Automated study of YGL202W: study_YGL202W.pl, study_YGL202W/
- Automated study of YGR248W: study_YGR248W.pl, study_YGR248W/
- Automated study of YHR163W: study_YHR163W.pl, study_YHR163W/
- Automated study of YIL033C: study_YIL033C.pl, study_YIL033C/
- Automated study of YJL045W: study_YJL045W.pl, study_YJL045W/
- Automated study of YJL060W: study_YJL060W.pl, study_YJL060W/
- Automated study of YJL218W: study_YJL218W.pl, study_YJL218W/
- Automated study of YLL060C: study_YLL060C.pl, study_YLL060C/
- Automated study of YLR017W: study_YLR017W.pl, study_YLR017W/
- Automated study of YLR070C: study_YLR070C.pl, study_YLR070C/
- Automated study of YLR209C: study_YLR209C.pl, study_YLR209C/
- Automated study of YMR020W: study_YMR020W.pl, study_YMR020W/
- Automated study of YNR027W: study_YNR027W.pl, study_YNR027W/
- Automated study of YNR034W: study_YNR034W.pl, study_YNR034W/
- Automated study of YNR073C: study_YNR073C.pl, study_YNR073C/
- Automated study of YPR121W: study_YPR121W.pl, study_YPR121W/
- Manual study of genes
encoding orphan enzymes by external wet and dry biology
- Manual study of genes
encoding orphan enzymes by wet biology
- Investigation into the reuse of formalised experiment information.
- The resources for the Robot Scientist investigations. (note: the Datalog files have links to these files).
- The click-through example of the Datalog formalism: Automated
study of enzyme EC2.6.1.39. Version for Internet Explorer
6. Colour version for all
other browsers. Version
without JavaScript (non-interactive).
- LABORS - an ontolology for the LABOratory automated Robot Scientists. The ontology defines only is-a hierarchy of the classes used for the description of the robot scientist investigations and a set of the relations for the datalog representation. LABORS.owl 33K
- Pictures of the Robot Scientist Adam.
- Figures.
Author contributions
Authors listed alphabetically:
AI software (EB, KEW); automated experimentation (ADAM); bioinformatics
(KEW, ML); comparative genomics (PP, SGO); database (AC, AS); growth
curve analysis (ML, MY, JR); hardware (AC, AS, JR); manual experiments
(AS, MM, MY, WA); ontology (AC, LNS, ML); statistics and data analysis
(AC, AS, ML). RDK conceived the idea, directed the work and drafted the
ms.