Aberystwyth provides excellent opportunities for instrumentalists.

The University's symphony orchestra, Philomusica, concentrates on music of the nineteenth and twentieth centuries. This large orchestra enjoys an excellent reputation and has worked with soloists of international standing, including pianist John Lill and harpist Catrin Finch. The University Sinfonia is a chamber orchestra that comes together on a semi-casual basis to enjoy smaller repertoire. Also on a more informal level, the University runs weekly string, guitar and saxophone groups, Simply Strings, Guitar Night and Saxophony.

The University Concert Band offers wind, brass and percussion players the chance to experience the full range of the wind band repertoire. It provides a musical opening for both advanced and less experienced musicians and gives two concerts a year. Aberystwyth Silver Band is a local brass band with a busy concert calendar and it offers a warm welcome to students.