Module Information

The module will begin with a section outlining the key principles of regulated gene expression and cell signaling together with lectures covering recurring themes throughout development and oncogenesis (cancer formation) such as cell migration and programmed cell death.

In the section on the development of the early embryo we will examine how signals and differential gene expression are important for determining the basic body pattern of embryos as diverse as those of a fly and a human, determining the fates of individual cells in the embryo, and regulating the movements of cells required to form a complex organism.

Cell fate (differentiation) and movement are two key factors in the development of cancer and, in the final part of the module, we will examine how problems with signaling and differential gene expression can lead to cancer and show how many of the process that are features of early development are also crucial for the growth and spread of cancer. How this understanding impacts on treatments and outcomes will also be discussed.

Plant molecular cell biology will also be discussed focusing on special aspects of signaling and gene expression. The experimental and commercial manipulation of these will be addressed.

Two lectures will be set aside to allow staff to discuss relevant topical subjects. This will vary from year to year depending on recent research. It may involve IBERS staff talking about their own research work or be based on events in the media.

Workshops will use a variety of video, virtual and data interpretation exercises to reinforce and expand on the taught material. In addition students will work in groups to develop websites based on cancer molecular biology topics.

The module will also feature a 2 hour session involving an invited speaker who will talk about her or his work in a field related to the topic and discuss career paths with students.