Dr Iain Chalmers

PhD, FHEA

Dr Iain Chalmers

Senior Lecturer

Department of Life Sciences

Contact Details

Profile

2022-present

Senior Lecturer in Veterinary Biosciences, Department of Life Sciences, Aberstwyth University, UK

2013-2022
Lecturer in Veterinary Biosciences, IBERS, Aberstwyth University, UK
2010-2013
EU-funded Post-Doctoral Research Associate, IBERS, Aberystwyth University, UK
2008-2009
Research Technician, IBERS, Aberystwyth University, UK
2002-2009
Wellcome Trust PhD programme, under supervision of Dr. Karl Hoffmann, Department of Pathology, University of Cambridge, UK
1998-2002
BSc (Hons.) Degree in Immunology, Edinburgh University, UK

Teaching

Module Coordinator
Lecturer
Tutor
Moderator
Coordinator
Grader

Research

My research focuses on the identification and characterisation of helminth proteins essential to the parasites survival in the host. The aim of this research is to discover novel vaccine candidates/drug targets and to also gain a deeper understanding of host/parasite interactions. Using bioinformatic approaches, my research also examines the evolution of gene families (such as the SmVAL family) across parasitic and non-parasitic species.

Responsibilities

Degree Programme Coordinator BSc Veterinary Bisociences

Publications

Padalino, G, Celatka, C, Rienhoff Jr., HY, Kalin, JH, Cole, PA, Lassalle, D, Forde-Thomas, J, Chalmers, I, Brancale, A, Grunau, C & Hoffmann, K 2023, 'Chemical modulation of Schistosoma mansoni lysine specific demethylase 1 (SmLSD1) induces wide-scale biological and epigenomic changes', Wellcome Open Research, vol. 8, no. 146, 146. 10.12688/wellcomeopenres.18826.1
Oettle, RC, Dickinson, HA, Fitzsimmons, CM, Sacko, M, Tukahebwa, EM, Chalmers, IW, Wilson, S & Loke, P (ed.) 2023, 'Protective human IgE responses are promoted by comparable life-cycle dependent Tegument Allergen-Like expression in Schistosoma haematobium and Schistosoma mansoni infection', PLoS Pathogens, vol. 19, no. 5, e1011037. 10.1371/journal.ppat.1011037, 10.17863/CAM.91264
White, R, Sotillo, J, Ancarola, ME, Borup, A, Boysen, AT, Brindley, PJ, Buzás, EI, Cavallero, S, Chaiyadet, S, Chalmers, IW, Cucher, MA, Dagenais, M, Davis, CN, Devaney, E, Duque-Correa, MA, Eichenberger, RM, Fontenla, S, Gasan, TA, Hokke, CH, Kosanovic, M, Kuipers, ME, Laha, T, Loukas, A, Maizels, RM, Marcilla, A, Mazanec, H, Morphew, RM, Neophytou, K, Nguyen, LT, Nolte-'t Hoen, E, Povelones, M, Robinson, MW, Rojas, A, Schabussova, I, Smits, HH, Sungpradit, S, Tritten, L, Whitehead, B, Zakeri, A, Nejsum, P, Buck, AH & Hoffmann, KF 2023, 'Special considerations for studies of extracellular vesicles from parasitic helminths: A community-led roadmap to increase rigour and reproducibility', Journal of Extracellular Vesicles, vol. 12, no. 1, 12298. 10.1002/jev2.12298
Davey, SD, Chalmers, IW, Fernandez-Fuentes, N, Swain, MT, Smith, D, Abbas Abidi, SM, Saifullah, MK, Raman, M, Ravikumar, G, McVeigh, P, Maule, AG, Brophy, PM & Morphew, RM 2022, 'In silico characterisation of the complete Ly6 protein family in Fasciola gigantica supported through transcriptomics of the newly-excysted juveniles', Molecular Omics, vol. 18, no. 1, pp. 45-56. 10.1039/D1MO00254F
Hulme, BJ, Geyer, KK, Forde-Thomas, JE, Padalino, G, Phillips, DW, Ittiprasert, W, Karinshak, SE, Mann, VH, Chalmers, IW, Brindley, PJ, Hokke, CH & Hoffmann, KF 2022, 'Schistosoma mansoni α-N-acetylgalactosaminidase (SmNAGAL) regulates coordinated parasite movement and egg production', PLoS Pathogens, vol. 18, no. 1, e1009828. 10.1371/journal.ppat.1009828
More publications on the Research Portal