Dr Amanda Gibson BSc (Hons), PhD, AFEA

Dr Amanda Gibson

Lecturer Innate Immunology Sêr Cymru

Department of Life Sciences

Contact Details

Profile

Amanda is a member of the Ser Cymru team within the Centre for Excellence in Bovine Tuberculosis based in Carwyn James Building.

Her current research activities surround the understanding of host-pathogen interaction at the very early stages of infection leading to disease progression – specifically to investigate the interaction of M. bovis with the innate immune system of the bovine host. Amanda's research activities are supported by a strong background in immunology and most recently comprehensive training in mycobacteriology.

Centre for Excellence in Bovine Tuberculosis research program is underpinned by 3 main themes: 

  1. Fundamental understanding of early innate immune events leading to infectious disease
  2. Understanding the role of Mycobacterial genetic strain diversity on immune interaction and disease progression
  3. Development of novel paired diagnostics and vaccine technologies

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Publications

Bartens, MC, Willcocks, S, Werling, D & Gibson, AJ 2024, 'Respiratory bioenergetics is enhanced in human, but not bovine macrophages after exposure to M. bovis PPD: Exploratory insights into overall similar Cellular Metabolic Profiles', Innate Immunity, vol. 30, no. 6-8, pp. 136-149. 10.1177/17534259241296630
Holder, A, Kolakowski, J, Rosentreter, C, Knuepfer, E, Jégouzo, SAF, Rosenwasser, O, Harris, H, Baumgaertel, L, Gibson, A & Werling, D 2023, 'Characterisation of the bovine C-type lectin receptor Mincle and potential evidence for an endogenous ligand', Frontiers in Immunology, vol. 14, 1189587. 10.3389/fimmu.2023.1189587
Frosini, S-M, Gallow, G, Gibson, A, Menezes, J, Pomba, C & Loeffler, A 2023, 'Detecting mecA in Faecal Samples: A Tool for Assessing Carriage of Meticillin-Resistant Staphylococci in Pets and Owners in the Microbiological ‘Fast Age’?', Microbiology Research, vol. 14, no. 1, pp. 60-66. 10.3390/microbiolres14010005
Gibson, AJ, Stiens, J, Passmore, IJ, Faulkner, V, Miculob, J, Willcocks, S, Coad, M, Berg, S, Werling, D, Wren, BW, Nobeli, I, Villarreal-Ramos, B & Kendall, SL 2022, 'Defining the Genes Required for Survival of Mycobacterium bovis in the Bovine Host Offers Novel Insights into the Genetic Basis of Survival of Pathogenic Mycobacteria', mBio, vol. 13, no. 4. 10.1128/mbio.00672-22, 10.5281/zenodo.6576716
Bunting, M, Challice, B, Gibson, A & van Winden, S 2021, 'In Vitro Supplementation of Copper Modulates the Functional Th1/Th2 Phenotype of Peripheral Blood Mononuclear Cells in Cattle', Animals, vol. 11, no. 9, 2739, pp. e2739. 10.3390/ani11092739
More publications on the Research Portal